Gene description for HSPA1A
Gene name	heat shock protein family A (Hsp70) member 1A
Gene symbol	HSPA1A
Other names/aliases	HEL-S-103 HSP70 HSP70-1 HSP70-1A HSP70-2 HSP70.1 HSP70.2 HSP70I HSP72 HSPA1
Species	Homo sapiens
Experiment description of studies that identified HSPA1A in Pancreatic cancer cells
1 Experiment ID 3421 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name MIA PaCa-2 - Elution 7-9 Isolation/purification methods Centrifugal ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 3422 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name MIA PaCa-2 - Elution 10-12 Isolation/purification methods Centrifugal ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 3423 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name MIA PaCa-2 - Elution 13-15 Isolation/purification methods Centrifugal ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
4 Experiment ID 3424 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name MIA PaCa-2 - Elution 16-18 Isolation/purification methods Centrifugal ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 3426 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name MIA PaCa-2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
6 Experiment ID 3427 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name MIA PaCa-2 Isolation/purification methods Differential centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
7 Experiment ID 3436 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name AsPC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
8 Experiment ID 3449 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name PANC-1 Isolation/purification methods Differential centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
9 Experiment ID 3450 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name PANC-1 Isolation/purification methods Differential centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
10 Experiment ID 3451 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name PANC-1 - KD Isolation/purification methods Differential centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
11 Experiment ID 3452 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name PANC-1 - KD Isolation/purification methods Differential centrifugation ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
12 Experiment ID 3453 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32341770    Organism Homo sapiens Experiment description DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Authors Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ. Journal name J Extracell Vesicles Publication year 2020 Sample Pancreatic cancer cells Sample name PANC-1 - KD Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
13 Experiment ID 2678 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name PANC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
14 Experiment ID 2679 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name MiaPaCa-2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
15 Experiment ID 2680 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name Capan-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
16 Experiment ID 2681 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name SW-1990 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
17 Experiment ID 2682 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name PPCL-68 (PDX) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
18 Experiment ID 2683 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name PPCL-46 (PDX) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
19 Experiment ID 2686 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name PANC-1 Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
20 Experiment ID 2687 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name MiaPaCa-2 Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
21 Experiment ID 2688 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name Capan-1 Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
22 Experiment ID 2689 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name SW-1990 Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
23 Experiment ID 2690 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name PPCL-68 (PDX) Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
24 Experiment ID 2691 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic cancer cells Sample name PPCL-46 (PDX) Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
25 Experiment ID 3346 Identified molecule protein Extracellular vesicle type Supermeres MISEV EV-like nanoparticles Identification method Mass spectrometry PubMed ID 34887515    Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic cancer cells Sample name PANC-1 Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry ELISA EV-TRACK -